William Clark writes to his nephew, John Hite Clark, from St. Louis, Missouri, regarding land and his mercantile business, especially his desire to engage in business with John and William's brother, Edmund, who expressed an interest in joining them. Discusses education matters regarding Joshua Fry's school and tuition for William Morrison of Kaskaskia's son.
Clark writes his brother Jonathan from St. Louis about the land he wants to sell in Clark County, Indiana, and the state of his finances involving his mercantile pursuits and land. Mentions the whereabouts and health of various Clark family members, including M. Lewis who is sick with worms.
Includes an 1 April 1810 account between Ann Maupin and Audubon & Rozier with a note from William C. Galt that Audubon would not deduct the cost of a pair of shoes. The second account from 1 April 1810 is with Beall for clothing. Both accounts are written by John J. Audubon and signed by both Audubon and Rozier.