William Clark writes to his brother Jonathan from the Corps of Discovery's first winter camp, reporting on events since parting with him below the Falls of the Ohio. He reports on an illness he has suffered, occurences at Fort Massac, the confluence of the Ohio and Mississippi Rivers, Kaskaskia, and establishing winter quarters at Wood River.
Clark writes his brother Jonathan from Louisville, reporting the party's arrival but also the unfortunate death of one of Jonathan's horses. He reports on a variety of land business, a school in their neighborhood starting, and beginning work on Jonathan's house.
William Clark writes his brother Jonathan from Redstone Landing [present Brownsville, Pennsylvania] on the Monongahela River updating him on the status of the trip moving Jonathan's enslaved people and some household goods and animals from Spotsylvania County, Virginia, to Jefferson County, Kentucky, ahead of Jonathan's family moving there later in the year. He provides specific information on the difficulties and costs encountered regarding the roads, weather, and enslaved people.